New paper on engineering tools for gram-negative thermophile published in Microbial Biotechnology

Our lab has successfully developed genetic engineering tools for Caldimonas thermodepolymerans DSM15344, a promising thermophilic bacterium for sustainable bioplastic production. We established homologous recombination and transposon-based genome editing protocols for this bacterium. We also engineered the AI01 chassis strain and a ΔphaC mutant, paving the way for deeper insights into PHA biosynthesis. These advances mark a crucial step toward domesticating thermophiles for bioeconomic applications. You can read the full study here: https://doi.org/10.1111/1751-7915.70103