Microbial Bioengineering Laboratory

Research group of Pavel Dvořák (Section of Microbiology, Department of Experimental Biology)

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Our current research areas

Engineering bacterial metabolism

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Designer catalytic scaffolds on bacterial surfaces                                                     

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Synthetic bacterial consortia                                          

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About the laboratory

We engineer bacteria and their metabolic and regulatory pathways for biotechnology and educate new generations of microbiologists/bioengineers at Masaryk University. Our long-term ambition is to combine microbiology with molecular biology, biochemistry, and bioinformatics, and work on interdisciplinary projects that contribute to the fundamental knowledge of the microbial systems studied but also have significant application potential.

The main research topic of the laboratory is microbial metabolism and physiology and their engineering for the biotechnological conversion of organic and synthetic waste materials, such as lignocellulosic residues or petroleum-based plastics, into valuable chemicals (biomaterials, biofuels, or pharmaceuticals). The safe and robust microbial strains are used as host organisms for harsh biocatalytic tasks.

For detailed insight into the microbial metabolism and physiology and for more efficient valorization of substrates from waste materials, we modify microorganisms and their biochemical pathways using state-of-the-art methods of synthetic biology, metabolic and protein engineering.

Our mission

We want to foster the scientific curiosity and societal responsibility of our students, stimulate better public awareness of microbial biotechnologies and their role in the knowledge-based bioeconomy, and perform excellent innovative research that will contribute to the sustainable development of our society.

Courses for students

The laboratory delivers a course and practical classes in Special Methods for Analysis of Microorganisms (Bi6721 and Bi6721c) and a course Introduction to the Metabolic Engineering and Synthetic Biology of Microorganisms (Bi7034) for undergraduate students.

Contact

Pavel Dvořák, Ph.D.
Head of the laboratory

E-mail: pdvorak@sci.muni.cz
Phone:  +420 549 49 3396

Adress

We have been supported by

Pavel is a proud holder of the Masaryk Award in Science and Humanities (MASH Junior) by the Grant Agency of Masaryk University (GAMU)

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